The Defense Production Act (DPA) Title III office is committed to ensuring resilient, robust domestic supply chains to reduce reliance on foreign manufacturing and correct domestic shortfalls in the defense industrial base. The DPA Title III office works in partnership with the Uniformed services, other government agencies, and industry to identify areas where critical industrial capacity is insufficient to meet U.S. defense and commercial needs. The office partners with U.S. private industry to mitigate gaps in the domestic supply chain using grants, purchase commitments, loans, or loan guarantees. The DPA Title III office is comprised of subject matter experts across a wide variety of investment areas, acquisition professionals, skilled program managers, and data analytics and audit professionals.

The Distributed Bioindustrial Manufacturing Program (DBIMP) aims to advance biotechnology as part of efforts to strengthen and build the resiliency of America's defense industrial base and secure its supply chains. Biomanufacturing has the potential to support the U.S. military and our allies and partners by generating needed materials — from fuels and chemicals to food and medical supplies — where and when our forces need them has significant implications for our military. 

E3: Economy, Energy and Environment is a federal technical assistance framework helping communities, manufacturers, and manufacturing supply chains adapt and thrive in today's green economy. The U.S. Environmental Protection Agency and five other federal agencies have pooled their resources to support small and medium-sized manufacturers with customized assessments. E3 is helping communities across the country reduce pollution and energy use while increasing profits and creating new job opportunities.

The Hollings Manufacturing Extension Partnership (MEP) is based at the National Institute of Standards and Technology. The National Program Office (NIST MEP) provides the federal government funding for the MEP National Network^™. The MEP National Network comprises the National Institute of Standards and Technology’s Manufacturing Extension Partnership, the 51 MEP Centers located in all 50 states and Puerto Rico, the MEP Advisory Board, MEP Center boards, and the Foundation for Manufacturing Excellence, as well as over 1,440 trusted advisors and experts at approximately 460 MEP service locations. The MEP National Network's strength is in its partnerships. Through its collaborations at the federal, state and local level, MEP Centers work with manufacturers to develop new products and customers, expand and diversify markets, adopt new technology, and enhance value within supply chains. The MEP Program serves as a bridge to other organizations and federal research labs that share a passion for enhancing the manufacturing community. 

The Made in America Office (MIAO) website is designed to promote transparency in federal procurement by enabling manufacturers and other parties to easily identify opportunities and relevant market intelligence to those interested in doing business with the U.S. government. This website provides centralized information on past and pending waivers of Made in America laws, information from which is used to support U.S. manufacturing and more resilient supply chains.

Initial information on historical waivers as well as current waivers resulting from initial implementation of Executive Order 14005: Ensuring the Future Is Made in All of America by All of America’s Workers is also available. 

The Manufacturing Capability Expansion and Investment Prioritization (MCEIP) Office oversees the execution of the Defense Production Act Investments (DPAI) and Innovation Capability and Modernization (ICAM) portfolios, utilizing all available authorities to address the challenge and incentivize industry.

Manufacturing USA was created in 2014 to secure U.S. global leadership in advanced manufacturing by connecting people, ideas, and technology. Manufacturing USA institutes convene business competitors, academic institutions, and other stakeholders to test applications of new technology, create new products, reduce cost and risk, and enable the manufacturing workforce with the skills of the future. Key initiatives include future manufacturing supply chains, , manufacturing workforce development, advanced manufacturing technology leadership, COVID-19 manufacturing recovery, and clean energy manufacturing.

The Biopharmaceutical Manufacturing Preparedness Consortium (BioMaP-Consortium) supports the Biomedical Advanced Research and Development Authority (BARDA) and is comprised of industry partners across the drug and vaccine manufacturing supply chain, including manufacturers of required raw materials and consumables, developers of innovative manufacturing technologies, and suppliers of fill finish services. This consortium seeks to expand the industrial and manufacturing base for medical countermeasures to include the requisite capabilities, flexibilities, and strategies to secure needed medical supplies to meet the nation’s public health preparedness and response requirements.

Manufacturing and Energy Supply Chains (MESC) plays a critical and unique role in catalyzing investments in America’s energy future to support the re-shoring, skilling, and scaling of U.S. manufacturing across energy supply chains. MESC addresses critical vulnerabilities in U.S. energy supply chains, serves as the frontline of clean energy deployment, and accelerates America’s transition to a resilient, equitable energy future through direct investments in manufacturing capacity and workforce development. MESC also develops and provides the energy supply chain focused analytical tools needed to inform programs and investments across the U.S. Department of Energy, the U.S. government, and the private sector by identifying gaps, vulnerabilities, and other needs across U.S. clean energy supply chains.

The Clean Energy Manufacturing Innovation Institute for Reducing Embodied-energy And Decreasing Emissions (REMADE), a Manufacturing USA Institute, focuses on early stage applied research towards innovations that could dramatically reduce the energy required to manufacture key materials and improve overall manufacturing energy efficiency through increased material reuse, recycling, and remanufacturing. REMADE is the only national institute focused entirely on developing innovative technologies to accelerate the U.S.’s transition to a Circular Economy. In partnership with industry, academia, trade organizations, and national laboratories, REMADE enables early-stage applied research and development that will create jobs, dramatically reduce embodied energy and greenhouse gas emissions, and increase the supply and use of recycled materials.

The U.S. Environmental Protection Agency’s SmartWay program helps companies advance supply chain sustainability by measuring, benchmarking, and improving freight transportation efficiency.